College, Historic Buildings & Museums
- Historic Down Town Village of Paint Lick
- The Denny House
Arts & Antiques
- Liz's Thomas Studio – Family Photographer
- Hand Wood Crafts – Don Weber, woodworker and blacksmith
- Art Studio, soon to open
- Friends of Paint Lick – thrift shop
Agri-Tourism
- Lazy Eight Farm – organic vegetable farm
Bourbon, Wine & Beer Trails
- H. Gumbert Brewery (Home Brewery)
Out Door Adventures
- Paint Lick County Park
- Trail along Paint Lick Creek (open date TBD)
- TransAmerica Bicycle Trail – Section 10: Murphysboro, IL – Berea, KY
Hospital
- White House Clinic – Dr. John Belanger's office
Restaurants
- Solidago – Farm to table restaurant (open date TBD)